![]() The best tissue type match is usually with a family member (brother or sister). Just as there are many red cell groups (known as blood groups), there are different white cell groups (known as tissue types). Matching bone marrow donors and recipientsĪnybody aged between 18 and 45, who is in good health and with no history of cancer, can donate bone marrow. In practice, the chance of being selected as a donor is relatively small.Īs with blood donors, bone marrow donors must answer specific questions relating to the risk of passing infections to the person who receives the donation. When a person needs a transplant, several possible donors will attend for additional blood tests, to find the donor with the best match. The result is then put on a confidential computer record. If you are interested in donating bone marrow, you will go to an interview, and then you will give a blood sample for tissue typing. Doctors can check a person’s tissue type with a simple blood test. The donor must have the same tissue type as the recipient. Bone marrow donors are matched with people who need a transplant to survive. The donor marrow finds the bones and settles into the cavities.ĭonating bone marrow can save another person’s life. The donor’s bone marrow cells are then injected into a vein, just like a blood transfusion. In a transplant operation, the person receiving the marrow (recipient) is treated with a high dose of chemotherapy or radiotherapy to destroy their diseased cells. Blood transfusions can help, but in the most serious cases, the person will only respond to a bone marrow transplant. Defective immune system – some children are born with a defective immune system and are unable to fight disease.Blood transfusions may help for a time, but a severely affected person may die unless they receive a transplant of normal bone marrow Symptoms include weakness, fever and skin haemorrhages (bleeding). The person may have the condition at birth, or certain drugs, chemicals or radiation may be the cause. This happens mostly in people aged between 15 and 30. Aplastic anaemia – a person stops making blood.Reticulum cell sarcoma of bone – a cancerous tumour of the bone marrow, occurring more often in males than in females.Treatment includes chemotherapy (drugs) and radiotherapy, and sometimes a bone marrow transplant from a healthy compatible person Symptoms include anaemia, bruising and nose bleeds. Leukaemia – a cancer of the blood that starts in the bone marrow.There are a number of diseases that affect the bone marrow including: In some cases, the best treatment is a transplant of bone marrow donated by another person. This leaves the person unable to make the new blood cells they need to fight infection and recover. Some illnesses and treatments can destroy the bone marrow. Without bone marrow, our bodies could not produce the white cells we need to fight infection, the red blood cells we need to carry oxygen, and the platelets we need to stop bleeding. Healthy bone marrow releases blood cells into the bloodstream when they are mature and when required. Bone marrow is the spongy tissue in the hollow centres of a person’s long bones.
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